Rapamycin extend lifespan, improve health, reduce cancer incidence, improve cognitive function and increace activity.
About Rapamycin
Rapamycin was isolated in 1972 from a bacterium found on Easter Island, aka Rapa Nui – hence the name. For many years it was an obscure transplant drug but in the early 2000s was found to significantly extend the lifespan of worms, yeast, flies and mice. In one experiment, researchers gave rapamycin to a group of 20-month-old mice, equivalent to retirement-aged humans. They fed the mice small doses for three months, then took them off the drug and waited for them to die. Mice usually die aged around 30 months but the drugged ones lived an extra 2 months on average. The final survivor died more than two years after the start of the experiment, at the ripe old age of 3 years and 8 months – the equivalent of around 140 in human years.
Rapamycin For Dogs — The Kaeberlein Study
The recent Kaeberlein study on 24 companion dogs at UW showed that….
- Rapamycin significantly improved heart function—Even more interesting, the improvement was greatest in those patients with more severe heart disease. According to the authors, these results suggest that rapamycin use in older dogs can actually reverse age-related declines in heart function. Now that’s a statement you don’t hear every day.
- There were no apparent adverse effects during the 10 week study period.
- 70% of the owners whose dogs received the higher rapamycin dose felt that their dogs were more active while on rapamycin, as did 40% of those whose dogs received the lower dose. In fairness, about 25% of the owners who gave their pets a placebo reported the same thing, but still…
- Similarly, 20%-40% of owners felt their dogs were more affectionate while being given rapamycin. The authors suggest that this could be due to the anti-inflammatory effects of rapamycin helping to reduce pain in arthritic pets.
Dr. Kaeberlein’s excitement over these findings prompted him to begin a wider study dubbed the Dog Aging Project.
"Rapamycin seems to have the ability to 'reset' immune function by reducing the increase in chronic inflammation that goes along with aging," Dr. Matt Kaeberlein of the Dog Aging Project says according to Yahoo. "This also seems to have benefits beyond the immune system in all sorts of tissues and organs."
Early tests on dogs, rats and mice show the drug is very effective at reducing the aging process. It was found to reduce age-related declines in mice, most notably in the heart, ovaries, brain and oral cavity. It was also found to boost the immune system's response to cancers and COVID-19.
The benefits
The most common benefits seen by owners who buy rapamycin for dogs are :
- more energy (72%),
- better spinal function (19%), and
- better cardiac function as noted by their veterinarian. (11%)
These studies show that….
Rapamycin is the future of dog anti-aging.
In The United States more than 32,000 dogs and their owners are already part of the Dog Aging Project. With an investment of 2.5$ million of tech entrepreneurs it's BOOMING!